Alcohols and polyols
- (1)
- (55)
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- (55)
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- (153)
- (1)
- (65)
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- (395)
- (6)
- (102)
- (21)
- (50)
- (31)
- (60)
- (13)
- (14)
- (1)
- (2)
- (1)
- (26)
- (6)
- (4)
- (1)
- (6)
- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
- (7)
- (10)
- (145)
- (114)
- (6)
- (5)
- (1)
- (1)
- (1)
- (1)
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- (1)
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- (7)
- (14)
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- (1)
- (6)
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- (1)
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- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (2)
- (4)
- (1)
- (2)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (2)
- (2)
- (2)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (15)
- (4)
- (5)
- (2)
- (5)
- (4)
- (33)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
- (2)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (17)
- (2)
- (6)
- (4)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
- (4)
- (1)
- (1)
- (3)
- (6)
- (11)
- (5)
- (3)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (2)
- (1)
- (3)
- (2)
- (10)
- (1)
- (2)
- (4)
- (4)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (1)
- (5)
- (3)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (5)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (9)
- (1)
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- (1)
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- (2)
- (1)
- (4)
- (2)
- (1)
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- (2)
- (11)
- (9)
- (1)
- (1)
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- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (1)
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- (8)
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- (3)
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- (8)
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- (1)
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- (9)
- (1)
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- (1)
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- (1)
- (1)
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- (9)
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- (1)
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- (3)
- (2)
- (1)
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- (18)
- (16)
- (1)
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- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
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- (11)
- (82)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
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- (20)
- (2)
- (2)
- (3)
- (67)
- (1)
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- (85)
- (1)
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- (72)
- (3)
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- (237)
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- (2)
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- (21)
- (278)
- (17)
- (1)
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- (273)
- (28)
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- (25)
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- (2)
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- (48)
- (3)
- (418)
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- (3)
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- (6)
- (3)
- (1)
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- (21)
- (2)
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- (1)
- (8)
- (2)
- (704)
- (11)
- (3)
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Filtered Search Results
Medchemexpress LLC Viloxazine hydrochloride | 35604-67-2 | MFCD00661100 | 98.9% | 273.76 | C13H20ClNO3 | 100MG
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Viloxazine hydrochloride is a research-grade small-molecule inhibitor of the norepinephrine transporter (NET) and a modulator of serotonin (5-HT) receptors, used in preclinical studies of neurotransmitter function and attention-deficit hyperactivity disorder (ADHD). It is supplied as a white to off-white solid with molecular formula C13H20ClNO3 and a molecular weight of 273.76 g/mol. For research use only; consult the product datasheet and safety data sheet for handling, storage, and hazard information.
- High purity (98.9%) suitable for analytical and preclinical studies.
- White to off-white solid form for easy handling and weighing.
- Molecular formula C13H20ClNO3 and molecular weight 273.76 g/mol.
- Stable under recommended storage: 4°C for solid; solutions may be stored at -20°C to -80°C per guidance.
- Datasheet and safety data sheet available for handling and regulatory compliance.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Ots186935 (hydrochloride) | 99.6% | 522.31 | 100 MG
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OTS186935 hydrochloride is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. It significantly inhibits tumor growth in mouse xenograft models without detectable toxicity and regulates the production of γ-H2AX in cancer cells. This compound has shown growth suppressive effects in human cancer cell line derived xenograft models.
- Potent SUV39H2 inhibitor
- Inhibits tumor growth in mouse xenograft models
- Regulates production of γ-H2AX in cancer cells
- Shows significant inhibition of tumor growth without detectable toxicity
- Inhibits A549 cell growth with an IC50 of 0.67 μM
- Exhibits growth suppressive effects in human cancer cell line derived xenograft models
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Midodrine (hydrochloride) | 43218-56-0 | 99.9% | 25 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Midodrine hydrochloride is a selective and orally active adrenergic α1-receptor agonist. It strengthens vascular contraction and can be used for research on cardiovascular diseases such as orthostatic hypotension.
- Strengthens vascular contraction
- Increases p-AMPK and PPARδ expression in C2C12, HL1, and HepG2 cells
- Increases Ca2+ in C2C12, HL1, and HepG2 cells
- Increases maximal mitochondrial oxidative phosphorylation and ATP content in C2C12 cells
- Reduces cellular lipid content in 3T3-L1 cells
- Reduces platelet-activating factor (Paf)-induced death in mice
- Shows anti-hypotensive effects in orthostatic hypotension rat models
- Relieves hypertension in spontaneously hypertensive rat models
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Leelamine hydrochloride | 16496-99-4 | 98.10% | 321.93 | 1 ML
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Leelamine hydrochloride is a tricyclic diterpene molecule extracted from the bark of pine trees. It acts as a cannabinoid receptor type 1 (CB1) agonist and an inhibitor of SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells, independent of androgen receptor status. It also suppresses the transcriptional activity of the androgen receptor, which regulates fatty acid synthesis.
- Acts as a cannabinoid receptor type 1 (CB1) agonist
- Inhibits SREBP1-regulated fatty acid/lipid synthesis in prostate cancer cells
- Suppresses the transcriptional activity of the androgen receptor
- Extracted from the bark of pine trees
- Appears as a white to off-white solid
- Store at -20°C in sealed conditions, away from moisture
- For storage in solvent, store at -80°C for 6 months, or -20°C for 1 month in sealed conditions, away from moisture
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Medchemexpress LLC Emixustat hydrochloride | 1141934-97-5 | MFCD28400873 | 99.3% | 299.84 | C16H26ClNO2 | 10 MG
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Emixustat hydrochloride is a research-grade RPE65 inhibitor and visual cycle modulator used to study retinal physiology and degenerative eye diseases. It inhibits retinol isomerization with low-nanomolar potency (IC50 ~4.4 nM) and is supplied as a hydrochloride salt for stability; it is used in both in vitro and in vivo retinal research models.
- Inhibits RPE65 with low-nanomolar potency.
- Modulates the visual cycle to reduce retinol isomerization.
- Suitable for in vitro and in vivo retinal research applications.
- Supplied as a hydrochloride salt for improved handling and stability.
- High purity by LCMS (reported >99%).
- Available in small-mass packaging for dosing and preclinical studies.
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Medchemexpress LLC Fedratinib (hydrochloride hydrate) | 1374744-69-0 | MFCD28137677 | >98.0% | 615.6 g/mol | C27H40Cl2N6O4S | 5 G
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Fedratinib hydrochloride hydrate is a potent, selective, ATP-competitive, orally active JAK2 inhibitor used for research into JAK-STAT signaling and myeloproliferative disorders. It inhibits JAK2 and JAK2V617F with IC50 ≈ 3 nM and has been shown to induce cancer cell apoptosis, supporting its use in preclinical pathway and disease-model studies.
- Potent JAK2 inhibition with IC50 of 3 nM
- High selectivity versus JAK1 and JAK3
- Suitable for myeloproliferative disorder and apoptosis research
- Hydrochloride hydrate form for stable handling
- Safety and handling details provided in the SDS
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Medchemexpress LLC Benzoic acid, 4-[4-[[(3R)-1-butyl-3-[(R)-cyclohexylhydroxymethyl]-2,5-dioxo-1,4,9-triazaspiro [5.5]undec-9-yl]methyl]phenoxy]-, hydrochloride (1:1) | 461023-63-2 | 99.9% | 614.17 | 25 MG
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Aplaviroc hydrochloride is a CCR5 antagonist derived from SDP, with IC50s ranging from 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and HIV-1MOKW. It is intended for research use only.
- Target: CCR5 antagonist
- Potency: Potent activity against wild-type R5 HIV-1 strains with IC50 values of 0.1 to 0.4 nM
- Mechanism: Suppresses infectivity and replication of HIV-1MDR variants at low concentrations (IC50 values of 0.4 to 0.6 nM)
- Binding Affinity: Binds to CCR5 with high affinity (Kd value of 2.9±1.0 nM)
- Inhibition: Potently blocks rgp120/sCD4 binding to CCR5 with an IC50 value of 2.7 nM
- In Vivo Efficacy: Suppresses R5 HIV-1 viremia in hu-PBMC-NOG mice at a dosage of 60 mg/kg
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Medchemexpress LLC Tipiracil hydrochloride | 183204-72-0 | 99.9% | C9H12Cl2N4O2 | 100 MG
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Tipiracil hydrochloride is a thymidine phosphorylase inhibitor (TPI) used for cancer research. It exhibits antiangiogenic effects and inhibits the proliferation of endothelial cells. This compound is also a potent inhibitor of thymidine phosphorylase, an enzyme that degrades FTD. It is for research use only.
- Thymidine phosphorylase inhibitor (TPI)
- Exhibits antiangiogenic effects
- Inhibits the proliferation of endothelial cells
- Potent inhibitor of thymidine phosphorylase
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Medchemexpress LLC W-7 (isomer hydrochloride) | 69762-85-2 | 99.7% | 377.33 | C16H22Cl2N2O2S | 50 MG
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W-7 (isomer hydrochloride) is a hydrochloride salt provided as a solid research reagent that acts as a calmodulin antagonist. It is used in biochemical and cellular studies to probe calmodulin-dependent signaling and enzyme activity; handle and store according to the supplier SDS for safety and stability.
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Medchemexpress LLC Oxyfedrine hydrochloride | 16777-42-7 | MFCD01695148 | 99.9% | 349.85 g/mol | C19H24ClNO3 | 1 ML
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Oxyfedrine hydrochloride is a β-adrenoreceptor agonist supplied as a ready-to-use 10 mM solution in DMSO (1 mL) for research applications. The accurately prepared solution simplifies assay setup and reduces measurement variability. Storage and handling recommendations are provided to maintain product stability.
- Prepared 10 mM solution in DMSO, 1 mL.
- High purity (99.9% by HPLC).
- Suitable for in vitro assays and compound screening.
- Includes storage and stability guidance for solvent and solid forms.
- Molecular formula C19H24ClNO3; molecular weight 349.85 g/mol.
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Medchemexpress LLC Ceftiofur hydrochloride | 103980-44-5 | 98.4% | C19H18ClN5O7S3 | 1 ML
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Ceftiofur hydrochloride is a potent cell wall synthesis inhibitor that targets bacterial penicillin-binding proteins (PBPs). It exerts bactericidal effects by inhibiting bacterial cell wall peptidoglycan synthesis, leading to cell lysis. Additionally, it possesses anti-inflammatory properties, inhibiting NF-κB and MAPKs, which reduces the secretion of pro-inflammatory cytokines such as TNF-α, IL-1β, and IL-6. This compound has been shown to improve survival rates in endotoxemia models.
- Targets bacterial penicillin-binding proteins (PBPs)
- Inhibits bacterial cell wall peptidoglycan synthesis
- Induces bacterial cell lysis
- Reduces secretion of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6)
- Inhibits phosphorylation of ERK, JNK, and p38
- Blocks nuclear translocation of NF-κB p65
- Improves survival in endotoxemia models
- Cited in 4 scientific publications
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Medchemexpress LLC Bambuterol hydrochloride | 81732-46-9 | 99.9% | 403.90 | 50 MG
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Bambuterol hydrochloride is a long-acting beta-adrenoceptor agonist (LABA) that is used to treat asthma; it is also a proagent of terbutaline.
- Acts as a long-acting beta-adrenoceptor agonist (LABA)
- Used in the treatment of asthma
- Functions as a proagent of terbutaline
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Medchemexpress LLC Fadrozole hydrochloride hemihydrate | 176702-70-8 | 99.6% | 268.74 | 25 MG
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Fadrozole hydrochloride hemihydrate is an orally active, potent, selective, and nonsteroidal aromatase inhibitor, with an IC50 of 6.4 nM. It inhibits the production of estrogen and progesterone, with IC50 values of 0.03 and 120 μM, respectively. This compound shows prevention of spontaneous tumors and can be used for research on estrogen-dependent diseases and cancer.
- Orally active
- Potent, selective, and nonsteroidal aromatase inhibitor (IC50 of 6.4 nM)
- Inhibits estrogen production (IC50 of 0.03 μM)
- Inhibits progesterone production (IC50 of 120 μM)
- Prevents spontaneous tumors
- Useful for research of estrogen-dependent diseases and cancer
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Medchemexpress LLC 7H-pyrrolo[2,3-d]pyrimidin-4-amine, N-butyl-N-ethyl-2,5,6-trimethyl-7-(trimethylphenyl) hydrochloride | 220953-69-5 | MFCD05664721 | 99.9% | 415.01 g/mol | C24H35ClN4 | 50 MG
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Antalarmin hydrochloride is a research-grade, non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist supplied as a white to light yellow solid for preclinical research. It is used to study stress-response pathways, CRH/CRF signaling, anxiety-like behavior, and inflammation models. The compound is provided at high purity and supplied in small mg-scale pack sizes suitable for laboratory use.
- Non-peptide CRHR1 antagonist used in stress and neuroendocrine research.
- High purity for reliable experimental results.
- Solid form, easy to weigh and formulate.
- Available in mg-scale pack sizes for preclinical studies.
- Includes datasheet, certificate of analysis, and safety data sheet documentation.
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Medchemexpress LLC CHK1-IN-4 hydrochloride | 00-00-0 | 480.75 g/mol | C18H19BrClN7O2 | 5 MG
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CHK1-IN-4 hydrochloride is the hydrochloride salt of a small-molecule inhibitor of checkpoint kinase 1 (CHK1). It is used in preclinical biochemical and cell-based studies to inhibit CHK1 phosphorylation and evaluate antitumor activity. Supplied as a solid with defined solubility and storage recommendations for research use.
- Potent checkpoint kinase 1 (CHK1) inhibitor active in tumor cells.
- Hydrochloride salt form for improved solubility and handling.
- Solid material; soluble in DMSO at 5 mg/mL with ultrasonic and warming.
- Storage: in solvent -80°C for up to 6 months; sealed -20°C for up to 1 month.
- Supplied in small research pack sizes suitable for preclinical studies.
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